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肖斐青年研究员

日期：2022-02-15 点击数：来源：

邮箱：xiao_fei@fudan.edu.cn

研究方向: 外周组织与中枢互作调控代谢稳态的机制

经历简介：

教育经历：

2007-2012 中国科学院营养科学研究所，博士

2003-2007南昌大学，学士

工作经历：

2022-至今 bwin必赢，青年研究员

2014-2021中国科学院上海营养与健康研究所，副研究员

2012-2014 中国科学院营养科学研究所，博士后

荣誉和奖励：

2018年入选上海市青年科技启明星计划

2016年获上海市自然科学三等奖（排名第三）

2016年入选中国科学院青年创新促进会会员

2016年获得赛诺菲·中科院上海生命科学研究院优秀青年人才奖励基金

2013年获得赛诺菲·中科院上海生命科学研究院优秀博士后人才奖励基金

2012年获得“上海市普通高等学校优秀毕业生”称号

主持项目：

国家自然科学基金委面上项目四项

国家自然科学基金委青年科学基金项目

中国博士后科学基金特别资助

中国博士后科学基金面上资助

中国科学院上海生命科学研究院博士后领域前沿项目

代表性论文：

1. Fei Xiao^#, Haizhou Jiang^#, Zi Li, Xiaoxue Jiang, Shanghai Chen, Yuguo Niu, Hanrui Yin, Yousheng Shu, Bo Peng, Wei Lu, Xiaoying Li, Zhigang Li, Shujue Lan, Xiaoyan Xu, Feifan Guo* (2023). Reduced hepatic bradykinin degradation accounts for cold-induced BAT thermogenesis and WAT browning in male mice, Nature Communications, 14:2523, DOI：10.1038/s41467-023-38141-0.

https://www.nature.com/articles/s41467-023-38141-0

2. Fei Xiao#, Jiali Deng#, Fuxin Jiao, Xiaoming Hu, Haizhou Jiang, Feixiang Yuan, Shanghai Chen, Yuguo Niu, Xiaoxue Jiang, Feifan Guo* (2022). Hepatic cytokine-inducible SH2-containing protein (CISH) regulates gluconeogenesis via cAMP-responsive element binding protein (CREB). FASEB J. 2022 Oct;36(10):e22541.

https://pubmed.ncbi.nlm.nih.gov/36083102/

3. Fei Xiao, Feifan Guo* (2021). Impacts of essential amino acids on energy balance, Molecular Metabolism, Nov 14;101393.

https://www.sciencedirect.com/science/article/pii/S2212877821002489?via%3Dihub

4. Jiali Deng, Yajie Guo, Feixiang Yuan, Shanghai Chen, Hanrui Yin, Xiaoxue Jiang, Fuxin Jiao, Fenfen Wang, Hongbin Ji, Guohong Hu, Hao Ying, Yan Chen, Qiwei Zhai, Fei Xiao*, Feifan Guo* (2020). Autophagy inhibition prevents glucocorticoid-increased adiposity via suppressing BAT whitening, Autophagy, 16(3):451-465.

https://www.tandfonline.com/doi/full/10.1080/15548627.2019.1628537

5. Fei Xiao#, Yajie Guo#, Jiali Deng, Feixiang Yuan, Yuzhong Xiao, Lijian Hui, Yu Li, Zhimin Hu, Yuncai Zhou, Kai Li, Xiao Han, Qichen Fang, Weiping Jia, Yan Chen, Hao Ying, Qiwei Zhai, Shanghai Chen, Feifan Guo* (2019). Hepatic c-Jun regulates glucose metabolism via FGF21 and modulates body temperature through the neural signals, Molecular Metabolism, 20:138-148.

https://www.sciencedirect.com/science/article/pii/S2212877818309761?via%3Dihub

6. Fei Xiao#, Jiali Deng#, Yajie Guo, Yuguo Niu, Feixiang Yuan, Junjie Yu, Shanghai Chen , Feifan Guo* (2016). BTG1 ameliorates liver steatosis by decreasing stearoyl-CoA desaturase 1 (SCD1) abundance and altering hepatic lipid metabolism, Science Signaling, 9(428): ra50.

https://www.science.org/doi/10.1126/scisignal.aad8581?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

7. Fei Xiao, Jiali Deng, Junjie Yu, Yajie Guo, Shanghai Chen, Feifan Guo* (2016). A novel function of B-cell translocation gene 1 (BTG1) in the regulation of hepatic insulin sensitivity in mice via c-Jun, FASEB Journal, 30(1):348-359.

https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.15-278689

8. Fei Xiao, Ying Du, Ziquan Lv, Shanghai Chen, Jianmin Zhu, Hongguang Sheng, Feifan Guo* (2016). Effects of essential amino acids on lipid metabolism in mice and humans, Journal of Molecular Endocrinology, 57(4):223-231.

https://jme.bioscientifica.com/view/journals/jme/57/4/223.xml

9. Fei Xiao#, Junjie Yu#, Bin Liu, Yajie Guo, Kai Li, Jiali Deng, Jin Zhang, Chunxia Wang, Shanghai Chen, Ying Du, Yingli Lu, Yuzhong Xiao, Zhou Zhang, Feifan Guo* (2014). A novel function of MicroRNA 130a-3p in hepatic insulin sensitivity and liver steatosis, Diabetes, 63(8): 2631-2642.

https://diabetesjournals.org/diabetes/article/63/8/2631/15652/A-Novel-Function-of-MicroRNA-130a-3p-in-Hepatic

10. Fei Xiao#, Tingting Xia#, Ziquan Lv#, Qian Zhang, Yuzhong Xiao, Junjie Yu, Hao Liu, Jiali Deng, Yajie Guo, Chunxia Wang, Kai Li, Bin Liu, Shanghai Chen, Feifan Guo* (2014). Central prolactin receptors (PRLRs) regulate hepatic insulin sensitivity in mice via signal transducer and activator of transcription 5 (STAT5) and the vagus nerve, Diabetologia, 57(10): 2136-44.

https://link.springer.com/article/10.1007%2Fs00125-014-3336-3

11. Fei Xiao, Junjie Yu, Yajie Guo, Jiali Deng, Kai Li, Ying Du, Shanghai Chen, Jianmin Zhu*, Hongguang Sheng*, Feifan Guo* (2014). Effects of individual branched-chain amino acids deprivation on insulin sensitivity and glucose metabolism in mice, Metabolism-Clinical and Experimental, 63(6):841-50.