沈夏 专任副研究员

日期:2020-11-16 点击数: 来源:

邮箱:shenxia@@fudan.edu.cn

研究方向:代谢组学与多组学整合,肿瘤代谢与免疫


教育经历

2021-2023      bwin必赢     博士后

2015-2021,中国科学院上海营养与健康研究所 理学博士


代表性研究成果和学术奖励情况

一、代表性论著

  1. Xia Shen, Can Wang, Ningning Liang, Zhen Liu, Xinde Li, Zheng-Jiang Zhu, Tony R. Merriman, Nicola Dalbeth, Robert Terkeltaub, Changgui Li, and Huiyong Yin (2021). "Serum metabolomics identifies dysregulated pathways and potential metabolic biomarkers for hyperuricemia and gout." Arthritis & Rheumatology.

  2. Mao Zhang, Yingying Huang, Jiaomeng Pan, Chen Sang, Youpei Lin, Liangqing Dong, Xia Shen, Yingcheng Wu, Guohe Song, Shuyi Ji, Fen Liu, Mengcheng Wang, Yuyan Zheng, Sirui Zhang, Zefeng Wang, Jianke Ren, Daming Gao, Jian Zhou, Jia Fan, Wu Wei*, Jian Lin*, Qiang Gao. "An Inflammatory Checkpoint Generated by IL1RN Splicing Offers Therapeutic Opportunity for KRAS-Mutant Intrahepatic Cholangiocarcinoma."Cancer Discovery 13.10 (2023): 2248-2269

  3. Guizhu Liu, Qian Liu, Naifu Wan, Xia Shen, Hui Cui, Cheng Dong, Xu Zhang, Huiyong Yin, Jian Wang, Colin Funk, and Ying Yu. Cardio-Protection by Peroxidase Activity of Prostaglandin H Synthases in Ischemia-Reperfusion Injury. Circulation 147.19 (2023): 1467-1470.

  4. Zijian Yang, Cong Yan, Jiaqiang Ma, Panpan Peng, Xuelian Ren, Shangli Cai, Xia Shen, Yingcheng Wu, Shu Zhang, Xiaoying Wang, Shuangjian Qiu, Jian Zhou, Jia Fan, He Huang, Qiang Gao. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma. Nature Metabolism 5, 61–79 (2023).

  5. Guijun Liu, Ningning Wang, Cunzhen Zhang, Min Li, Xuxiao He, Chunzhao Yin, Qiaochu Tu, Xia Shen, Lili Zhang, Jingwen Lv, Yongqiang Wang, Huimin Jiang, Shiting Chen, Nan Li, Yongzhen Tao, Huiyong Yin. (2021). Fructose‐1, 6‐bisphosphate aldolase B depletion promotes hepatocellular carcinogenesis through activating insulin receptor signaling and lipogenesis. Hepatology, 74(6), 3037-3055.

  6. MinLi;Xuxiao He WG, Hongming Yu, Shicheng Zhang , Ningning Wang, Guijun Liu, Rina Sa, Xia Shen, Huiyong Yin. Aldolase B suppresses hepatocellular carcinogenesis by inhibiting G6PD and pentose phosphate pathways. Nature Cancer. 2020.

二、科研项目

中国博士后科学基金面上资助


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