孙立婷 青年副研究员

日期:2021-11-05 点击数: 来源:

邮箱litingsun@fudan.edu.cn


研究方向 通过实验动物疼痛模型及痛觉行为学检测,研究慢性疼痛的发病机制,并通过基因操控、药物调控或硬膜外脊髓电刺激等手段进行镇痛干预研究。


经历简介

2000-2005年,本科毕业于中国农业大学,动物医学系

2007-2012年,经国家公派博士毕业于英国爱丁堡大学,皇家兽医系

2013-2018年,在香港大学李嘉诚医学院进行博士后研究,麻醉学系

2018-2021年,在同济大学医学院任职副研究员

202111月至今,在bwin必赢任职青年副研究员。


主要从事慢性痛的发病机制及小分子化药、脊髓电刺激镇痛调控机制的研究,研究成果发表在Progress in NeurobiologyBritish journal of AnaesthesiaPainMolecular PainEuropean journal of PainNeuropharmacology等国际学术期刊上。主持国家自然科学基金青年项目1项,发明专利2项。


代表论文

1) Fu Yan, Sun Liting, Zhu Fengting, Xia Wei, Wen Ting, Xia Ruilong, Yu Xin, Xu Dan, Peng Changgeng. Ectopic expression of Nav1.7 in spinal dorsal horn neurons induced by NGF contributes to neuropathic pain in a mouse spinal cord injury model. Front Mol Neurosci. 2023,16:1091096.

2) Sun Liting,* Peng Changgeng, Joosten Elbert A., Cheung Chi Wai, Tan Fei, Jiang Wencheng, Shen Xiafeng.* Spinal Cord Stimulation and Treatment of Peripheral or Central Neuropathic Pain: Mechanisms and Clinical Application, Neural Plasticity, 2021:5607898.

3) Sun Liting,# Xia Ruilong,# Jiang Jingwen, Wen Ting, Huang, Zhuoya, Qian Ran, Zhang Ming-Dong, Zhou Mingcheng, Peng Changgeng.* MicroRNA-96 is required to prevent allodynia by repressing voltage-gated sodium channels in spinal cord, Progress in Neurobiology, 2021, 102024.

4) Tai, W., Sun, L., Li, H., Gu, P., Joosten, E.A., Cheung, C.W.* Additive effects of Environmental Enrichment and Ketamine on Neuropathic Pain Relief by Reducing Glutamatergic Activation in Spinal Cord Injury in Rat. Frontiers in Neuroscience, 2021, 15:635187.

5) Sun Liting, Fleetwood-Walker, Mitchell Rory, Joosten Elbert A., Cheung Chi Wai*. Prolonged analgesia by spinal cord stimulation following a spinal injury associated with activation of adult neural progenitors. Pain Practice, 2020, 20(8):859-877.

6) Wong Stanley Sau-Ching#, Sun Liting#, Qiu Qiu, Gu Pan, Li Qing, Wang Xiao-Min, and Cheung Chi Wai*. Propofol attenuates postoperative hyperalgesia via regulating spinal GluN2B-p38MAPK/EPAC1 pathway in an animal model of postoperative pain. European Journal of Pain, 2019,23:812-822.

7) Sun Liting, Li Haobo, Tai Lydia Wai, Gu Pan, Cheung Chi Wai*. Adiponectin regulates thermal nociception in a mouse model of neuropathic pain, British Journal of Anaesthesia, 2018, 120(6):1356-1367.

8) Gu Pan, Pan Zhi Qiang, Wang Xiao Min, Sun Liting, Cheung Chi Wai*. Histone deacetylase 5 (HDAC5) regulates neuropathic pain through SRY-related HMG-box 10 (SOX10)-dependent mechanism in mice. Pain, 2018, 159(3):526-539.

9) Qiu Qiu #, Sun Liting #Wang Xiao Min, Lo Amy, Wong Kar Lok, Gu Pan, Wong Stanley, Cheung Chi Wai*. Propofol produces preventive analgesia via GluN2B-containing NMDA Receptor/ERK1/2 signaling pathway in a rat model of inflammatory pain, Molecular Pain, 2017, 13: 1-13.

10) Sun Liting, Tai Lydia Wai, Qiu Qiu, Luo Xin, Mitchell Rory, Fleetwood-Walker Sue, Joosten Elbert A., Cheung Chi Wai*. Endocannabinoid activation of CB1 receptors contributes to long-lasting reversal of neuropathic pain by repetitive spinal cord stimulation. European Journal of Pain, 2017, 21(5): 804-814.


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